Osteonecrosis of the Knee (Avascular Necrosis) — assessment and management in Brisbane
Osteonecrosis of the knee occurs when the blood supply to a segment of bone in the thighbone or shinbone is disrupted. It most often affects the inside of the knee and can be mistaken for ordinary osteoarthritis.

Osteonecrosis of the knee develops when the blood supply to a segment of bone — most often the medial femoral condyle on the inside of the knee — is disrupted. The affected bone dies and can collapse, and the overlying cartilage collapses with it, leading to arthritis of the joint.

Assessment focuses on distinguishing this from ordinary knee osteoarthritis, meniscal pathology and subchondral stress fracture. The history is often the clue: abrupt, well-localised medial knee pain in an older adult, or knee pain in someone on prolonged oral corticosteroids or with a transplant history. As with the hip, plain X-rays are usually normal early on, so ongoing symptoms with a normal X-ray warrant further assessment. MRI is the definitive investigation.

First-line care for small, early lesions is usually analgesia, protected weight-bearing, an unloader brace where appropriate, and a physiotherapy program to maintain quadriceps strength and joint range. Larger lesions, collapse, or pain that does not settle require orthopaedic assessment. The clinic’s regenerative and shockwave treatments do not have an established role in osteonecrosis, and the appropriate pathway here is timely diagnosis and specialist referral.

Common symptoms

  • Sudden or well-localised pain on the inside of the knee
  • Pain on standing and weight-bearing
  • Swelling over the front and inside of the knee
  • Tenderness to touch and reduced range of motion
Evidence-informed treatment summary

How our treatment options may fit for Osteonecrosis of the Knee (Avascular Necrosis)

The options below include the treatments offered at The Back Pain Doctor. Listing a treatment does not mean it is recommended for this condition. The evidence, likely benefit and role of each option are considered against the diagnosis, examination findings, imaging where appropriate, patient goals, risks, cost and alternatives.

Foundation

Diagnosis, education and progressive rehabilitation

This is the starting point for most musculoskeletal conditions.

The priority is to identify the likely pain generator, explain the condition clearly, modify aggravating load and build a realistic plan to restore strength, movement and confidence.

Evidence is condition-specific; it is not a universal pain treatment.

Shockwave is best framed as an adjunct where the diagnosis fits. It is generally more established for selected tendon and plantar heel pain presentations than for many joint or nerve conditions.

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Evidence varies substantially by condition, tissue and preparation method.

PRP may be discussed in selected tendon or joint presentations. It should not be presented as a guaranteed regenerative treatment, and uncertainty, cost and alternatives should be discussed.

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Best used for specific inflammatory or irritable pain generators, usually for short-term relief.

An injection may help when a joint, bursa, tendon sheath or other defined structure is driving symptoms. It is not a cure and needs to be weighed against risks, recurrence and the need for rehabilitation.

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Clinical evidence is still developing and guideline support is limited.

EMTT may be discussed as an adjunct in selected presentations, but should be presented with clear uncertainty and never as a replacement for diagnosis, load management or rehabilitation.

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Selected cases

Prolotherapy

Evidence is condition-specific and generally less established than exercise-based care.

Prolotherapy may be considered in carefully selected chronic ligament, tendon or joint-related pain presentations, but it is not a first-line treatment.

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Most relevant when focal myofascial pain is a clear contributor.

Trigger point treatment may reduce pain from focal muscle spasm or myofascial tenderness. It should be paired with movement restoration, strength work and recurrence prevention.

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Relevant only when the history and examination support nerve irritation or entrapment.

Nerve-focused treatment may be discussed when there is a plausible peripheral nerve pain generator. Progressive weakness, major neurological deficit or red flags require a different pathway.

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This is general information only. Suitability is assessed individually. Treatments with limited or condition-dependent evidence may still be discussed, but only with clear explanation of uncertainty, expected benefit, risks, cost and alternatives. Red flags, progressive neurological symptoms or suspected serious pathology require a different pathway.

Frequently asked questions

How is knee osteonecrosis diagnosed?
Diagnosis is based on symptoms, examination and imaging. X-rays are usually normal in the early stages, so a normal X-ray does not exclude it. MRI detects early bone changes, shows the extent of involvement, and may identify disease in the opposite knee before symptoms appear.
How is it different from knee osteoarthritis?
Osteonecrosis often causes pain that starts abruptly and is sharply localised to the inside of the knee, rather than the gradual, diffuse ache typical of osteoarthritis. It is more common over the age of 60 and in women, and can progress to arthritis if not identified early.
What does treatment involve?
Early or small lesions may be managed non-surgically with analgesia, protected weight-bearing, an unloader brace and a physiotherapy program. Larger lesions or persistent pain usually require surgical assessment, so orthopaedic referral is appropriate.

Ready for a clearer plan for your back or musculoskeletal pain?

Book an assessment with Dr Joshua Hatch.

Your assessment focuses on understanding the likely source of your pain and the most appropriate non-surgical options for your diagnosis, with the aim of reducing pain and improving function.

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