Osteonecrosis of the knee occurs when the blood supply to a segment of bone in the thighbone or shinbone is disrupted. It most often affects the inside of the knee and can be mistaken for ordinary osteoarthritis.
Osteonecrosis of the knee develops when the blood supply to a segment of bone — most often the medial femoral condyle on the inside of the knee — is disrupted. The affected bone dies and can collapse, and the overlying cartilage collapses with it, leading to arthritis of the joint.
Assessment focuses on distinguishing this from ordinary knee osteoarthritis, meniscal pathology and subchondral stress fracture. The history is often the clue: abrupt, well-localised medial knee pain in an older adult, or knee pain in someone on prolonged oral corticosteroids or with a transplant history. As with the hip, plain X-rays are usually normal early on, so ongoing symptoms with a normal X-ray warrant further assessment. MRI is the definitive investigation.
First-line care for small, early lesions is usually analgesia, protected weight-bearing, an unloader brace where appropriate, and a physiotherapy program to maintain quadriceps strength and joint range. Larger lesions, collapse, or pain that does not settle require orthopaedic assessment. The clinic’s regenerative and shockwave treatments do not have an established role in osteonecrosis, and the appropriate pathway here is timely diagnosis and specialist referral.