Hydrodissection uses fluid, placed under ultrasound guidance, to separate a nerve from the tissue tethering or compressing it. It is used for peripheral nerve entrapment, and the clearest evidence is in mild to moderate carpal tunnel syndrome.

What it can help with

  • Carpal tunnel syndrome (mild to moderate)
  • Cubital and ulnar tunnel syndrome
  • Other peripheral nerve entrapments identified on ultrasound
  • Nerve pain following surgery or injury, where scar tissue is implicated

Suitability depends on your individual diagnosis and is assessed at consultation.

Nerve hydrodissection is an ultrasound-guided procedure that uses fluid to separate an irritated nerve from the tissue around it. It is used where the assessment points to a peripheral nerve as the pain generator rather than a joint, tendon or muscle.

It sits at stage five of our treatment pathway. That is not a ranking of usefulness — for the right problem it is one of the better-evidenced things we do. It is a statement about relevance: most musculoskeletal pain is not nerve-driven, so this stage applies to a minority of people, and identifying that minority is part of the assessment.

Carpal tunnel syndrome is the clearest indication, with randomised trial support in mild to moderate cases. Where compression is severe, or there is muscle wasting or significant conduction loss, surgery is the appropriate treatment and we will refer you rather than inject.

How it works

A nerve needs to glide. Where it becomes tethered to the surrounding tissue or compressed within a tunnel, movement pulls on it, and the nerve becomes irritated and mechanically sensitive. Hydrodissection introduces fluid into the plane immediately around the nerve, separating it from the adjacent tissue and restoring some of that gliding.

The procedure is performed under ultrasound because the nerve must be seen for the whole injection. What is injected varies — commonly dextrose in saline, or saline with local anaesthetic. Corticosteroid can be used, but is not necessary for the mechanical effect and carries the longer-term considerations set out on our injections page.

What the evidence shows

Carpal tunnel syndrome is where the evidence is strongest. Randomised trials and systematic reviews support hydrodissection in mild to moderate carpal tunnel syndrome, with improvement in symptom scores, hand function and nerve conduction measures, and effects sustained across several months of follow-up in a number of studies. That places it among the better-evidenced options we offer at this stage of the pathway, and a reasonable step to consider before surgical decompression. Outside carpal tunnel syndrome the evidence thins considerably. Trials in other entrapments are small, and hydrodissection is not a treatment for osteoarthritis, tendinopathy or axial spinal pain — where it appears on those condition pages it is labelled "only if relevant", meaning only if assessment finds a separate nerve pain generator. Severe entrapment with muscle wasting or significant conduction loss needs a surgical opinion, not an injection, and we will say so.

What to expect

The nerve is scanned along its course and the site of compression identified. After skin preparation and local anaesthetic, a fine needle is guided to the nerve and fluid is placed around it in stages, with the separation watched on screen. The procedure usually takes ten to fifteen minutes. You can expect temporary numbness or tingling from the anaesthetic and mild local soreness for a day or two. Symptom change often develops over the following weeks rather than immediately, and a repeat procedure is sometimes discussed.

Frequently asked questions

Is hydrodissection an alternative to carpal tunnel surgery?
For mild to moderate carpal tunnel syndrome it is a reasonable option to consider before surgery, and the trial evidence supports it. For severe compression with muscle wasting or marked nerve conduction loss, surgical decompression remains the appropriate treatment and we will refer you.
What is injected around the nerve?
Commonly dextrose in saline, or saline with local anaesthetic. Corticosteroid can be used but is not required for the mechanical effect, and we prefer to avoid it where a non-steroid option will do.
Does it hurt?
Local anaesthetic is used, so the procedure is generally well tolerated. Temporary numbness or tingling is expected, and mild soreness for a day or two is common.
How long until I notice a difference?
Some people notice early change from the anaesthetic and the decompression itself; more often improvement develops over the following weeks. Night symptoms are frequently the first thing to settle.
Is it covered by Medicare?
The procedure is performed during a standard GP consultation and billed under the time-based GP consultation items, which attract a Medicare rebate. Consumables are charged separately. Appointments are not bulk billed, so an out-of-pocket gap applies.

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Your assessment focuses on understanding the likely source of your pain and the most appropriate non-surgical options for your diagnosis, with the aim of reducing pain and improving function.

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