PRP stands for platelet-rich plasma. A sample of your blood is processed to concentrate platelets, then the preparation is injected into a target joint, tendon or soft-tissue region.

The evidence for PRP varies by condition. It has been studied most in knee osteoarthritis and some tendon problems, but results are mixed. That is why the decision should be diagnosis-specific and realistic.

Before a PRP injection

Before treatment, the important question is whether PRP is a reasonable option for your problem. We consider the diagnosis, severity, previous treatment, goals, costs and alternatives.

You may be asked about medications, bleeding risk, infection, immune conditions and recent illness. Some medications can affect bleeding or inflammation, so medication advice should be individualised rather than guessed.

What happens on the day?

A blood sample is taken and processed. The injection is then performed into the target area, often with image guidance depending on the location. The appointment includes preparation time as well as the injection itself.

After treatment

It is common to have temporary soreness. The early phase is usually about protecting the area from excessive load while avoiding unnecessary immobilisation. The next phase is a gradual return to loading or rehabilitation.

PRP does not remove the need for strength work, weight management, activity modification or other foundations of care. It is an adjunct, not a replacement for the plan.

When to seek help

Increasing redness, fever, severe escalating pain, or feeling unwell after an injection should be assessed promptly. These problems are uncommon but important.

You can read more on our PRP injections page.

The bottom line

PRP may be worth considering for selected musculoskeletal problems, but it should be used with realistic expectations and a clear aftercare plan.